Dip2c^em1(IMPC)Tcp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dip2c^em1(IMPC)Tcp
• Name: disco interacting protein 2 homolog C; endonuclease-mediated mutation 1, The Centre for Phenogenomics
• MGI ID: MGI:6279900
• Gene: Dip2c Location: Chr13:9326564-9718964 bp, + strand Genetic Position: Chr13, 3.7 cM, cytoband A1
• Alliance: Dip2c^em1(IMPC)Tcp page
• IMPC: Dip2c gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from project TCPR1261 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of GAACTTGCACTCGGAAGTAC targeting the 5' side and TCATGTGGTAGTAGTCACCT targeting the 3' side of a critical region. This resulted in a 530-bp deletion of Chr13 from 9560449 to 9560978 (GRCm38). (J:265051)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Dip2c Mutation: 119 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 3 reference(s)