Sec13^{em1(IMPC)Hmgu}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sec13^{em1(IMPC)Hmgu}
• Name: SEC13 homolog, nuclear pore and COPII coat complex component; endonuclease-mediated mutation 1, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:6279926
• Gene: Sec13 Location: Chr6:113705013-113717642 bp, - strand Genetic Position: Chr6, 52.84 cM, cytoband E3
• Alliance: Sec13^{em1(IMPC)Hmgu} page
• IMPC: Sec13 gene page

Mutation origin

• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from IMPC was generated at Helmholtz-Zentrum Muenchen by injecting CAS9 Protein and 4 guide sequences CCTGGGTCTTAGTTGTAGAAACC, CCTATTCACGGAATTTTAGCAGA, CCAAACTTGTCACCCTATTCACG, CCAGGTGGCTGGTCAAAGTACCC, which resulted in a Exon Deletion. (J:265051)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sec13 Mutation: 18 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 3 reference(s)