About   Help   FAQ
Phf6em2Azbi
Endonuclease-mediated Allele Detail
Summary
Symbol: Phf6em2Azbi
Name: PHD finger protein 6; endonuclease-mediated mutation 2, Azad Bonni
MGI ID: MGI:6280443
Gene: Phf6  Location: ChrX:52001143-52045820 bp, + strand  Genetic Position: ChrX, 29.28 cM, cytoband A4
Alliance: Phf6em2Azbi page
Mutation
origin
Strain of Origin:  (C57BL/6 x CBA)F2
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Insertion
 
Mutation detailsCRISPR/Cas9 technology generated a 1 bp insertion (G) at nucleotide 298 resulting in a frameshift mutation. Detailed molecular characterization confirmed this is a null allele. (J:271089)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Phf6 Mutation:  12 strains or lines available
References
Original:  J:271089 Cheng C, et al., Characterization of a Mouse Model of Borjeson-Forssman-Lehmann Syndrome. Cell Rep. 2018 Nov 6;25(6):1404-1414.e6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/19/2024
MGI 6.24
The Jackson Laboratory