Borcs7tm1Bhk
Targeted Allele Detail
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Symbol: |
Borcs7tm1Bhk |
Name: |
BLOC-1 related complex subunit 7; targeted mutation 1, Beverly H Koller |
MGI ID: |
MGI:6280949 |
Gene: |
Borcs7 Location: Chr19:46678345-46691821 bp, + strand Genetic Position: Chr19, 38.97 cM, cytoband D1
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Alliance: |
Borcs7tm1Bhk page
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Germline Transmission: |
Earliest citation of germline transmission:
J:271219
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129S6/SvEvTac
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A targeting vector was designed to replace the entire 13.3 kb of the gene, including the entire coding sequence, with a phosphoglycerate kinase-driven neomycin resistance gene. Homologous recombination results in deletion of a segment of chromosome 10 extending from 102,854,233-102,862,254 (GRCh38/hg38).
(J:271219)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Borcs7 Mutation: |
7 strains or lines available
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Original: |
J:271219 Snouwaert JN, et al., A Mutation in the Borcs7 Subunit of the Lysosome Regulatory BORC Complex Results in Motor Deficits and Dystrophic Axonopathy in Mice. Cell Rep. 2018 Jul 31;24(5):1254-1265 |
All: |
1 reference(s) |
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