Clptm1l^{tm1c(EUCOMM)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Clptm1l^{tm1c(EUCOMM)Wtsi}
• Name: CLPTM1-like; targeted mutation 1c, Wellcome Trust Sanger Institute
• MGI ID: MGI:6281108
• Synonyms: Clptm1l^flox
• Gene: Clptm1l Location: Chr13:73752125-73768724 bp, + strand Genetic Position: Chr13, 40.12 cM
• Alliance: Clptm1l^{tm1c(EUCOMM)Wtsi} page
• IMPC: Clptm1l gene page

Mutation origin

• Mutant Cell Line: EPD0460_2_E07
• Germline Transmission: Earliest citation of germline transmission: J:265892
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion Vector: L1L2_Bact_P
• Mutation details: The L1L2_Bact_P cassette was inserted at position 73753908 of Chromosome 13 upstream of the critical exon 3 (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of exon 3 at position 73754758. Exon 3 is thus flanked by loxP sites. Flp-mediated recombination removed the reporter and selection cassettes and left exon 3 floxed. (J:265892)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Clptm1l Mutation: 34 strains or lines available

References

• Original: J:265892 Trezise S, et al., Mining the Plasma Cell Transcriptome for Novel Cell Surface Proteins. Int J Mol Sci. 2018 Jul 24;19(8):2161
• All: 1 reference(s)