H2ab1^em1Ttas
Endonuclease-mediated Allele Detail

Summary

• Symbol: H2ab1^em1Ttas
• Name: H2A.B variant histone 1; endonuclease-mediated mutation 1, Tatiana A Soboleva
• MGI ID: MGI:6281555
• Synonyms: gm14290 X^delta10, gm14920 X^delta10
• Gene: H2ab1 Location: ChrX:115924454-115924801 bp, + strand Genetic Position: ChrX, 49.58 cM
• Alliance: H2ab1^em1Ttas page

Mutation origin

• Strain of Origin: FVB/NJArc

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• TALEN-targeting produced a deletion of 10 nucleotides. (J:271400)

Expression

In Mice Carrying this Mutation:

52018 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any H2ab1 Mutation: 1 strain or line available

References

• Original: J:271400 Anuar ND, et al., Gene editing of the multi-copy H2A.B gene and its importance for fertility. Genome Biol. 2019 Jan 31;20(1):23
• All: 1 reference(s)