Lrrc19^tm1Ryag
Targeted Allele Detail

Summary

• Symbol: Lrrc19^tm1Ryag
• Name: leucine rich repeat containing 19; targeted mutation 1, Rongcun Yang
• MGI ID: MGI:6281582
• Gene: Lrrc19 Location: Chr4:94524890-94538381 bp, - strand Genetic Position: Chr4, 43.34 cM
• Alliance: Lrrc19^tm1Ryag page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:271376
• Parent Cell Line: B6/BLU (ES Cell)
• Strain of Origin: C57BL/6NTac-Tg(HBB-lacZ)ALey/Ley

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A floxed neomycin resistance cassette replaced exons 2 through 4 and 304 bp of exon 5. (J:271376)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lrrc19 Mutation: 20 strains or lines available

References

• Original: J:271376 Su X, et al., LRRC19 expressed in the kidney induces TRAF2/6-mediated signals to prevent infection by uropathogenic bacteria. Nat Commun. 2014 Jul 16;5:4434
• All: 2 reference(s)