Fas^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Fas^m2Btlr
• Name: Fas cell surface death receptor; mutation 2, Bruce Beutler
• MGI ID: MGI:6283435
• Synonyms: bing
• Gene: Fas Location: Chr19:34268066-34305172 bp, + strand Genetic Position: Chr19, 29.48 cM
• Alliance: Fas^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced G to A transition at base pair 34,316,569 (v38) on chromosome 19, or base pair 24,659 in the GenBank genomic region NC_000085. The mutation corresponds to residue 379 in the mRNA sequence NM_007987 within exon 4 of 9 total exons. The mutation results in a glycine to aspartic acid substitution at position 108 (G108D) in the Fas protein. (J:271891)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fas Mutation: 82 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3608

References

• Original: J:271891 Zhong X, et al., Mutagenetix entry for bing. MGI Direct Data Submission. 2019
• All: 1 reference(s)