Pik3ap1^M3Btlr
Chemically induced Allele Detail

Summary

• Symbol: Pik3ap1^M3Btlr
• Name: phosphoinositide-3-kinase adaptor protein 1; mutation 3, Bruce Beutler
• MGI ID: MGI:6283640
• Synonyms: Pintail
• Gene: Pik3ap1 Location: Chr19:41260980-41373541 bp, - strand Genetic Position: Chr19, 34.61 cM, cytoband D1
• Alliance: Pik3ap1^M3Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transition at base pair 41,376,146 (v38) on chromosome 19, or base pair 8,925 in the GenBank genomic region NC_000085 encoding Pik3ap1. The mutation corresponds to residue 303 in the NM_031376.3 mRNA sequence in exon 2 of 17 total exons. The mutation results in a tyrosine to histidine substitution at position 45 (Y45H) in the B cell adaptor protein (BCAP) protein. (J:272019)
• Inheritance: Dominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pik3ap1 Mutation: 50 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3628

References

• Original: J:272019 Zhong X, et al., Mutagenetix entry for Pintail. MGI Direct Data Submission. 2019
• All: 1 reference(s)