Bach2^M1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Bach2^M1Btlr
• Name: BTB and CNC homology, basic leucine zipper transcription factor 2; mutation 1, Bruce Beutler
• MGI ID: MGI:6283665
• Synonyms: Magnificat
• Gene: Bach2 Location: Chr4:32238804-32586108 bp, + strand Genetic Position: Chr4, 14.02 cM, cytoband A4
• Alliance: Bach2^M1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to T transversion at base pair 32,563,324 (v38) on chromosome 4, or base pair 324,751 in the GenBank genomic region NC_000070. The mutation corresponds to residue 1,951 in the mRNA sequence NM_001109661 within exon 3 of 5 total exons. The mutation results in a glutamic acid to valine substitution at position 597 (E597V) in the BACH2 protein. (J:272023)
• Inheritance: Dominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bach2 Mutation: 46 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3232

References

• Original: J:272023 Zhong X, et al., Mutagenetix entry for Magnificat. MGI Direct Data Submission. 2019
• All: 1 reference(s)