Trpc1^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Trpc1^m1Btlr
• Name: transient receptor potential cation channel, subfamily C, member 1; mutation 1, Bruce Beutler
• MGI ID: MGI:6283669
• Synonyms: magnified
• Gene: Trpc1 Location: Chr9:95587135-95632428 bp, - strand Genetic Position: Chr9, 50.2 cM, cytoband E4
• Alliance: Trpc1^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to G transition at base pair 95,726,437 (v38) on chromosome 9, or base pair 23,951 in the GenBank genomic region NC_000075. The mutation corresponds to residue 1,271 in the mRNA sequence NM_178666 within exon 5 of 13 total exons. The mutation results in glutamic acid to glycine substitution at position 267 (E267G) in the TRPC1 protein. (J:272024)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trpc1 Mutation: 41 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3586

References

• Original: J:272024 Zhang Z, et al., Mutagenetix entry for magnified. MGI Direct Data Submission. 2019
• All: 1 reference(s)