Rag1^m4Btlr
Chemically induced Allele Detail

Summary

• Symbol: Rag1^m4Btlr
• Name: recombination activating 1; mutation 4, Bruce Beutler
• MGI ID: MGI:6283875
• Synonyms: defective
• Gene: Rag1 Location: Chr2:101468627-101479846 bp, - strand Genetic Position: Chr2, 53.88 cM
• Alliance: Rag1^m4Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: A to T transversion at base pair 101,642,710 (v38) on chromosome 2, or base pair 6,823 in the GenBank genomic region NC_000068. The mutation corresponds to residue 2,211 (c.2211A>T) in the mRNA sequence NM_009019.2 within exon 2 of 2 total exons. The mutation results in an arginine to tryptophan substitution at position 696 (p.R696W) in the RAG1 protein. (J:272094)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rag1 Mutation: 123 strains or lines available

References

• Original: J:272094 Zhong X, et al., Mutagenetix entry for defective. MGI Direct Data Submission. 2019
• All: 1 reference(s)