Tg(Tcra19,Tcrb19)#Stl
Transgene Detail

Summary

• Symbol: Tg(Tcra19,Tcrb19)#Stl
• Name: transgene insertion, Susumu Tonegawa
• MGI ID: MGI:6284341
• Transgene: Tg(Tcra19,Tcrb19)#Stl Location: unknown
• Alliance: Tg(Tcra19,Tcrb19)#Stl page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The transgene contains a recombined mouse Tcr locus from T cell clone 19, which recognizes the acetylated N-terminal 9-amino acid fragment of myelein basic protein (MBP). The pound symbol (#) is used when no line was specified and/or lines are pooled. (J:19795)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:19795 Lafaille JJ, et al., High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice. Cell. 1994 Aug 12;78(3):399-408
• All: 19 reference(s)