Klhl6^m4Btlr
Chemically induced Allele Detail

Summary

• Symbol: Klhl6^m4Btlr
• Name: kelch-like 6; mutation 4, Bruce Beutler
• MGI ID: MGI:6284782
• Synonyms: torres_del_paine
• Gene: Klhl6 Location: Chr16:19765242-19801766 bp, - strand Genetic Position: Chr16, 12.32 cM
• Alliance: Klhl6^m4Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to A transversion at base pair 19,948,127 (v38) on chromosome 16, or base pair 34,923 in the GenBank genomic region NC_000082 encoding Klhl6. The mutation corresponds to residue 1,562 in the mRNA sequence NM_183390 within exon 6 of 7 total exons. The mutation results in a cysteine to serine substitution at position 506 (C506S) in the KLHL6 protein. (J:272394)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Klhl6 Mutation: 48 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3773

References

• Original: J:272394 Zhong X, et al., Mutagenetix entry for torres_del_paine. MGI Direct Data Submission. 2019
• All: 1 reference(s)