Klhl6^M5Btlr
Chemically induced Allele Detail

Summary

• Symbol: Klhl6^M5Btlr
• Name: kelch-like 6; mutation 5, Bruce Beutler
• MGI ID: MGI:6284786
• Synonyms: Ascension
• Gene: Klhl6 Location: Chr16:19765242-19801766 bp, - strand Genetic Position: Chr16, 12.32 cM
• Alliance: Klhl6^M5Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to G transition at base pair 19,947,098 (v38) on chromosome 16, or base pair 35,952 in the GenBank genomic regionNC_000082encodingKlhl6.The mutation corresponds to residue 1,799 in the mRNA sequence NM_183390 within exon 7 of 7 total exons. The mutation results in a threonine to alanine substitution at position 585 (T585A) in the KLHL6 protein. (J:272395)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Klhl6 Mutation: 48 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3771

References

• Original: J:272395 Zhong X, et al., Mutagenetix entry for Ascension. MGI Direct Data Submission. 2019
• All: 1 reference(s)