About   Help   FAQ
Stk4m4Btlr
Chemically induced Allele Detail
Summary
Symbol: Stk4m4Btlr
Name: serine/threonine kinase 4; mutation 4, Bruce Beutler
MGI ID: MGI:6285558
Synonyms: sergeant
Gene: Stk4  Location: Chr2:163916033-163997444 bp, + strand  Genetic Position: Chr2, 84.6 cM, cytoband H3
Alliance: Stk4m4Btlr page
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Mutation
description
Allele Type:    Chemically induced (ENU) (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsENU-induced A to G transition at base pair 164,099,712 (v38) on chromosome 2, or base pair 25,600 in the GenBank genomic region NC_000068 encoding Stk4. The mutation corresponds to residue 922 in the mRNA sequence NM_021420 within exon 8 of 11 total exons. The mutation results in a serine to glycine substitution at position 283 (S283G) in the STK4 protein. (J:272536)
Inheritance:    Recessive
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Stk4 Mutation:  74 strains or lines available
Notes
https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3843
References
Original:  J:272536 Zhong X, et al., Mutagenetix entry for sergeant. MGI Direct Data Submission. 2019;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory