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Stk4m4Btlr
Chemically induced Allele Detail
Summary
Symbol: Stk4m4Btlr
Name: serine/threonine kinase 4; mutation 4, Bruce Beutler
MGI ID: MGI:6285558
Synonyms: sergeant
Gene: Stk4  Location: Chr2:163916033-163997444 bp, + strand  Genetic Position: Chr2, 84.6 cM, cytoband H3
Alliance: Stk4m4Btlr page
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Mutation
description
Allele Type:    Chemically induced (ENU) (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsENU-induced A to G transition at base pair 164,099,712 (v38) on chromosome 2, or base pair 25,600 in the GenBank genomic region NC_000068 encoding Stk4. The mutation corresponds to residue 922 in the mRNA sequence NM_021420 within exon 8 of 11 total exons. The mutation results in a serine to glycine substitution at position 283 (S283G) in the STK4 protein. (J:272536)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Stk4 Mutation:  74 strains or lines available
Notes
https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3843
References
Original:  J:272536 Zhong X, et al., Mutagenetix entry for sergeant. MGI Direct Data Submission. 2019;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory