About   Help   FAQ
PtprcM9Btlr
Chemically induced Allele Detail
Summary
Symbol: PtprcM9Btlr
Name: protein tyrosine phosphatase receptor type C; mutation 9, Bruce Beutler
MGI ID: MGI:6285650
Synonyms: Chor_muang
Gene: Ptprc  Location: Chr1:137990599-138103446 bp, - strand  Genetic Position: Chr1, 60.73 cM
Alliance: PtprcM9Btlr page
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Mutation
description
Allele Type:    Chemically induced (ENU) (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsENU-induced T to A transversion at base pair 138,113,562 (v38) on chromosome 1, or base pair 62,195 in the GenBank genomic region NC_000067 within the splice donor site of intron 9 (2-base pairs from exon 9). The effect of the mutation at the cDNA and protein levels has not been examined, but the mutation is predicted to result in the use of a cryptic site in intron 9. The resulting transcript would have a 53-base pair insertion of intron 9 that would cause an in-frame protein product beginning after amino acid 203 of the protein [which is normally 1,293 amino acids in length (isoform 1)], and termination after the inclusion of 13 aberrant amino acids. (J:272745)
Inheritance:    Semidominant
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ptprc Mutation:  189 strains or lines available
Notes
https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3902
References
Original:  J:272745 Zhong X, et al., Mutagenetix entry for Chor_muang. MGI Direct Data Submission. 2019;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory