PtprcM9Btlr
Chemically induced Allele Detail
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Symbol: |
PtprcM9Btlr |
Name: |
protein tyrosine phosphatase receptor type C; mutation 9, Bruce Beutler |
MGI ID: |
MGI:6285650 |
Synonyms: |
Chor_muang |
Gene: |
Ptprc Location: Chr1:137990599-138103446 bp, - strand Genetic Position: Chr1, 60.73 cM
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Alliance: |
PtprcM9Btlr page
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Strain of Origin: |
C57BL/6J
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Project Collection: |
Beutler Mutagenetix
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Allele Type: |
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Chemically induced (ENU) (Not Specified) |
Mutation: |
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Single point mutation
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Mutation details: ENU-induced T to A transversion at base pair 138,113,562 (v38) on chromosome 1, or base pair 62,195 in the GenBank genomic region NC_000067 within the splice donor site of intron 9 (2-base pairs from exon 9). The effect of the mutation at the cDNA and protein levels has not been examined, but the mutation is predicted to result in the use of a cryptic site in intron 9. The resulting transcript would have a 53-base pair insertion of intron 9 that would cause an in-frame protein product beginning after amino acid 203 of the protein [which is normally 1,293 amino acids in length (isoform 1)], and termination after the inclusion of 13 aberrant amino acids.
(J:272745)
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Inheritance: |
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Semidominant |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ptprc Mutation: |
189 strains or lines available
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https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3902
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Original: |
J:272745 Zhong X, et al., Mutagenetix entry for Chor_muang. MGI Direct Data Submission. 2019; |
All: |
1 reference(s) |
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