Rel^m3Btlr
Chemically induced Allele Detail

Summary

• Symbol: Rel^m3Btlr
• Name: reticuloendotheliosis oncogene; mutation 3, Bruce Beutler
• MGI ID: MGI:6285867
• Synonyms: giza
• Gene: Rel Location: Chr11:23686847-23720969 bp, - strand Genetic Position: Chr11, 14.36 cM
• Alliance: Rel^m3Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced C to T transition at base pair 23,757,010 (v38) on chromosome 11, or base pair 13,961 in the GenBank genomic region NC_000077. The mutation corresponds to residue 472 in the mRNA sequence NM_009044 within exon 3 of 10 total exons. The mutation results in a threonine to isoleucine substitution at position 64 (T64I) in the c-Rel protein. (J:272801)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rel Mutation: 45 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3994

References

• Original: J:272801 Zhong X, et al., Mutagenetix entry for giza. MGI Direct Data Submission. 2019
• All: 1 reference(s)