Fnip1^M3Btlr
Chemically induced Allele Detail

Summary

• Symbol: Fnip1^M3Btlr
• Name: folliculin interacting protein 1; mutation 3, Bruce Beutler
• MGI ID: MGI:6285877
• Synonyms: Normandy
• Gene: Fnip1 Location: Chr11:54329025-54409061 bp, + strand Genetic Position: Chr11, 32.13 cM
• Alliance: Fnip1^M3Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to A transversion at base pair 54,493,181 (v38) on chromosome 11, or base pair 55,037 in the GenBank genomic region NC_000077 within intron 9, 12-base pairs from exon 10 (out of 18 total exons). The effect of the mutation at the cDNA and protein levels has not been examined, but the mutation is predicted to not affect splicing. In case the mutation does affect splicing, the most likely aberrant splicing would result in skipping of the 202-base pair exon 10. The mutation would cause a frame-shifted protein product beginning after amino acid 305 of the protein, which is normally 1,165 amino acids in length, and termination after the inclusion of one aberrant amino acid. (J:272802)
• Inheritance: Dominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fnip1 Mutation: 60 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3746

References

• Original: J:272802 Zhong X, et al., Mutagenetix entry for Normandy. MGI Direct Data Submission. 2019
• All: 1 reference(s)