Atm^M4Btlr
Chemically induced Allele Detail

Summary

• Symbol: Atm^M4Btlr
• Name: ataxia telangiectasia mutated; mutation 4, Bruce Beutler
• MGI ID: MGI:6285928
• Synonyms: Strato
• Gene: Atm Location: Chr9:53350449-53448040 bp, - strand Genetic Position: Chr9, 29.12 cM, cytoband C-D
• Alliance: Atm^M4Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to G transition at base pair 53,503,018 (v38) on chromosome 9, or base pair 33,799 in the GenBank genomic region NC_000075. The mutation corresponds to residue 2,910 in the mRNA sequence NM_007499 within exon 18 of 64 total exons. The mutation results in an aspartic acid to glycine substitution at amino acid 924 (D924G) in the ATM protein. (J:272821)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atm Mutation: 170 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3672

References

• Original: J:272821 Zhong X, et al., Mutagenetix entry for Strato. MGI Direct Data Submission. 2019
• All: 1 reference(s)