Atm^m5Btlr
Chemically induced Allele Detail

Summary

• Symbol: Atm^m5Btlr
• Name: ataxia telangiectasia mutated; mutation 5, Bruce Beutler
• MGI ID: MGI:6285932
• Synonyms: osphere
• Gene: Atm Location: Chr9:53350449-53448040 bp, - strand Genetic Position: Chr9, 29.12 cM, cytoband C-D
• Alliance: Atm^m5Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to A transversion at base pair 53,479,673 (v38) on chromosome 9, or base pair 57,144 in the GenBank genomic region NC_000075. The mutation corresponds to residue 5,739 in the mRNA sequence NM_007499 within exon 36 of 64 total exons. The mutation results in a leucine to glutamine substitution at amino acid 1,867 (L1867Q) in the ATM protein. (J:272824)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atm Mutation: 170 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3671

References

• Original: J:272824 Zhong X, et al., Mutagenetix entry for osphere. MGI Direct Data Submission. 2019
• All: 1 reference(s)