Mdm4^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Mdm4^m2Btlr
• Name: transformed mouse 3T3 cell double minute 4; mutation 2, Bruce Beutler
• MGI ID: MGI:6285944
• Synonyms: Isla_nublar
• Gene: Mdm4 Location: Chr1:132913843-132958325 bp, - strand Genetic Position: Chr1, 57.75 cM, cytoband G-G
• Alliance: Mdm4^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transition at base pair 133,012,692 (v38) on chromosome 1, or base pair 17,896 in the GenBank genomic region NC_000067 encoding Mdm4. The mutation corresponds to residue 300 in the mRNA sequence NM_008575 within exon 3 of 12 total exons. The mutation results in a leucine to proline substitution at amino acid 34 (L34P) in the MDM4 protein. (J:272830)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mdm4 Mutation: 193 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3778

References

• Original: J:272830 Zhong X, et al., Mutagenetix entry for isla_nublar. MGI Direct Data Submission. 2019
• All: 1 reference(s)