Ebf1^M5Btlr
Chemically induced Allele Detail

Summary

• Symbol: Ebf1^M5Btlr
• Name: early B cell factor 1; mutation 5, Bruce Beutler
• MGI ID: MGI:6286040
• Synonyms: Befuddled
• Gene: Ebf1 Location: Chr11:44508144-44898918 bp, + strand Genetic Position: Chr11, 26.45 cM
• Alliance: Ebf1^M5Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to G transition at base pair 44,632,775 (v38) on chromosome 11, or base pair 14,676 in the GenBank genomic region NC_000077. The mutation corresponds to residue 515 in the mRNA sequence NM_001290709 within exon 5 of 16 total exons. The mutation results in a lysine to glutamic acid substitution at position 146 (K146E) in the EBF1 protein. (J:272841)
• Inheritance: Other (see notes)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ebf1 Mutation: 74 strains or lines available

Notes

Inheritance is unknown/not applicable. https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3739

References

• Original: J:272841 Zhong X, et al., Mutagenetix entry for Befuddled. MGI Direct Data Submission. 2019
• All: 1 reference(s)