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Zbtb1m2Btlr
Chemically induced Allele Detail
Summary
Symbol: Zbtb1m2Btlr
Name: zinc finger and BTB domain containing 1; mutation 2, Bruce Beutler
MGI ID: MGI:6286068
Synonyms: old_friend
Gene: Zbtb1  Location: Chr12:76417040-76443724 bp, + strand  Genetic Position: Chr12, 33.73 cM
Alliance: Zbtb1m2Btlr page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Chemically induced (ENU) (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsENU-induced C to T transition at base pair 76,385,891 (v38) on chromosome 12, or base pair 15,700 in the GenBank genomic region NC_000078. The mutation corresponds to residue 877 in the mRNA sequence NM_178666 within exon 2 of 2 total exons. The mutation results in an threonine to isoleucine substitution at position 217 (T217I) in the ZBTB1 protein. (J:272845)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Zbtb1 Mutation:  115 strains or lines available
Notes
https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3694
References
Original:  J:272845 Zhong X, et al., Mutagenetix entry for old_friend. MGI Direct Data Submission. 2019;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory