Tap2^M4Btlr
Chemically induced Allele Detail

Summary

• Symbol: Tap2^M4Btlr
• Name: transporter 2, ATP-binding cassette, sub-family B (MDR/TAP); mutation 4, Bruce Beutler
• MGI ID: MGI:6286077
• Synonyms: Palm
• Gene: Tap2 Location: Chr17:34423453-34435295 bp, + strand Genetic Position: Chr17, 17.98 cM
• Alliance: Tap2^M4Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced C to A transversion at base pair 34,215,940 (v38) on chromosome 17, or base pair 11,462 in the GenBank genomic region NC_000083 encoding Tap2. The mutation corresponds to residue 2,109 in the mRNA sequence NM_011530 within exon 12 of 12 total exons. The mutation results in an aspartic acid to glutamic acid substitution at position 652 (D652E) in the TAP2 protein. (J:272847)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tap2 Mutation: 28 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3850

References

• Original: J:272847 Zhong X, et al., Mutagenetix entry for Palm. MGI Direct Data Submission. 2019
• All: 1 reference(s)