Tnfsf13b^m3Btlr
Chemically induced Allele Detail

Summary

• Symbol: Tnfsf13b^m3Btlr
• Name: tumor necrosis factor (ligand) superfamily, member 13b; mutation 3, Bruce Beutler
• MGI ID: MGI:6286111
• Synonyms: arrested
• Gene: Tnfsf13b Location: Chr8:10056637-10086000 bp, + strand Genetic Position: Chr8, 4.55 cM
• Alliance: Tnfsf13b^m3Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to G transition at base pair 10,031,545 (v38) on chromosome 8, or base pair 25,343 in the GenBank genomic region NC_000074 encoding Tnfsf13b. The mutation corresponds to residue 916 in the mRNA sequence NM_033622 within exon 6 of 7 total exons. The mutation results in an isoleucine to valine substitution at position 236 (I236V) in isoform 1 of the BAFF protein. (J:272850)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tnfsf13b Mutation: 30 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3868

References

• Original: J:272850 Zhong X, et al., Mutagenetix entry for arrested. MGI Direct Data Submission. 2019
• All: 1 reference(s)