Inpp5d^m5Btlr
Chemically induced Allele Detail

Summary

• Symbol: Inpp5d^m5Btlr
• Name: inositol polyphosphate-5-phosphatase D; mutation 5, Bruce Beutler
• MGI ID: MGI:6286237
• Synonyms: pantone
• Gene: Inpp5d Location: Chr1:87548034-87648229 bp, + strand Genetic Position: Chr1, 44.44 cM, cytoband C5
• Alliance: Inpp5d^m5Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to A transversion at base pair 87,699,675 (v38) on chromosome 1, or base pair or 79,364 in the GenBank genomic region NC_000067. The mutation corresponds to residue 1,874 in the mRNA sequence NM_010566 within exon 15 of 27 total exons. The mutation results in a leucine to glutamine substitution at amino acid 566 (L566Q) in the SHIP-1 protein. (J:272856)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Inpp5d Mutation: 94 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3388

References

• Original: J:272856 Zhong X, et al., Mutagenetix entry for pantone. MGI Direct Data Submission. 2019
• All: 1 reference(s)