Pappa^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Pappa^m1Btlr
• Name: pregnancy-associated plasma protein A; mutation 1, Bruce Beutler
• MGI ID: MGI:6286271
• Synonyms: caer
• Gene: Pappa Location: Chr4:65042411-65275746 bp, + strand Genetic Position: Chr4, 34.14 cM
• Alliance: Pappa^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced C-to-A mutation at base pair 65,124,891 (GRCm38) on chromosome 4, or base pair 718 in the GenBank genomic region NC_000070. The mutation corresponds to residue 718 in the mRNA sequence NM_021362 within exon 1 of 22 total exons. The mutation results in a threonine to lysine substitution at position 117 (p.T117K) in the encoded peptide. (J:272859)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pappa Mutation: 72 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3577

References

• Original: J:272859 Zhang Z, et al., Mutagenetix entry for caer. MGI Direct Data Submission. 2019
• All: 3 reference(s)