Cd79b^M2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Cd79b^M2Btlr
• Name: CD79B antigen; mutation 2, Bruce Beutler
• MGI ID: MGI:6286293
• Synonyms: Jeju
• Gene: Cd79b Location: Chr11:106202167-106205388 bp, - strand Genetic Position: Chr11, 68.89 cM
• Alliance: Cd79b^M2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced G to A transition at base pair 106,312,713 (v38) on chromosome 11, or base pair 1,850 in the GenBank genomic region NC_000077. The mutation corresponds to residue 425 in the mRNA sequence NM_008339 within exon 3 of 6 total exons. The mutation results in a glycine to aspartic acid substitution at position 116 (G116D) in the CD79B protein. (J:272863)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd79b Mutation: 36 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=4029

References

• Original: J:272863 Zhong X, et al., Mutagenetix entry for Jeju. MGI Direct Data Submission. 2019
• All: 1 reference(s)