Polm^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Polm^m1Btlr
• Name: polymerase (DNA directed), mu; mutation 1, Bruce Beutler
• MGI ID: MGI:6286309
• Synonyms: gott
• Gene: Polm Location: Chr11:5777860-5788016 bp, - strand Genetic Position: Chr11, 3.87 cM
• Alliance: Polm^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transition at base pair 5,829,512 (v38) on chromosome 11, or base pair 8,831 in the GenBank genomic region NC_000077. The mutation corresponds to residue 1,550 in the mRNA sequence NM_017401 within exon 9 of 11 total exons. The mutation results in a phenylalanine to leucine substitution at position 429 (F429L) in the Polm protein. (J:272866)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Polm Mutation: 29 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3928

References

• Original: J:272866 Zhong X, et al., Mutagenetix entry for gott. MGI Direct Data Submission. 2019
• All: 1 reference(s)