Mirc23tm1.1Shbk
Targeted Allele Detail
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Symbol: |
Mirc23tm1.1Shbk |
Name: |
microRNA cluster 23, including Mir374b through Mir421; targeted mutation 1.1, Shin Kobayashi |
MGI ID: |
MGI:6287756 |
Synonyms: |
miRNA374/421 DKO |
Gene: |
Mirc23 Location: ChrX:102616527-102616760 bp Genetic Position: ChrX, Syntenic
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Germline Transmission: |
Earliest citation of germline transmission:
J:268562
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mirc23tm1.1Shbk involves 3 genes/genome features (Mir421, Mir374b, Mir374c)
View all
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Mutation details: An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of Mir374b. An additional loxP site was inserted downstream of Mir421. Cre-mediated mutation removed the selection cassette and the microRNAs.
(J:268562)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Mirc23 Mutation: |
1 strain or line available
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Original: |
J:268562 Hosoi Y, et al., Female mice lacking Ftx lncRNA exhibit impaired X-chromosome inactivation and a microphthalmia-like phenotype. Nat Commun. 2018 Sep 20;9(1):3829 |
All: |
1 reference(s) |
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