Specc1em1(IMPC)J
Endonuclease-mediated Allele Detail
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Symbol: |
Specc1em1(IMPC)J |
Name: |
sperm antigen with calponin homology and coiled-coil domains 1; endonuclease-mediated mutation 1, Jackson |
MGI ID: |
MGI:6294912 |
Gene: |
Specc1 Location: Chr11:61847589-62113839 bp, + strand Genetic Position: Chr11, 37.96 cM
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Alliance: |
Specc1em1(IMPC)J page
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IMPC: |
Specc1 gene page |
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Strain of Origin: |
C57BL/6NJ
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Project Collection: |
IMPC
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Allele Type: |
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Endonuclease-mediated (Null/knockout) |
Mutation: |
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Intragenic deletion
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Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences ACTGAGAAGATACCTAGAGG and GTAAATTACATCAGATGATA, which resulted in a 2002 bp deletion beginning at Chromosome 11 position 62,117,560 bp and ending after 62,119,561 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000238537 (exon 4) and 419 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 95 and early truncation 10 amino acids later.
(J:188991)
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Inheritance: |
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Not Specified |
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Original: |
J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012; |
All: |
2 reference(s) |
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