Scyl1^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Scyl1^m1Btlr
• Name: SCY1-like 1 (S. cerevisiae); mutation 1, Bruce Beutler
• MGI ID: MGI:6303927
• Synonyms: spartacus
• Gene: Scyl1 Location: Chr19:5808450-5821461 bp, - strand Genetic Position: Chr19, 4.34 cM
• Alliance: Scyl1^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced G to T transversion at base pair 5,760,826 (v38) on chromosome 19, or base pair 10,589 in the GenBank genomic region NC_000085. The mutation corresponds to residue 1,551 (c.1551G>T) in the mRNA sequence NM_023912.3 within exon 10 of 17 total exons. The mutation results in a valine to phenylalanine substitution at position 488 (p.V488F) in the SCYL1 protein. (J:274649)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Scyl1 Mutation: 21 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=4030

References

• Original: J:274649 Regmi N, et al., Mutagenetix entry for spartacus. MGI Direct Data Submission. 2019
• All: 1 reference(s)