Mbtps1^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Mbtps1^m2Btlr
• Name: membrane-bound transcription factor peptidase, site 1; mutation 2, Bruce Beutler
• MGI ID: MGI:6304283
• Synonyms: muskrat
• Gene: Mbtps1 Location: Chr8:120234895-120285474 bp, - strand Genetic Position: Chr8, 67.85 cM, cytoband E1
• Alliance: Mbtps1^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced C to T transition at base pair 119,538,137 (v38) on chromosome 8, or base pair 20,689 in the GenBank genomic region NC_000074. The mutation corresponds to residue 1,609 in the mRNA sequence NM_019709 within exon 9 of 24 total exons. The mutation results in a proline to serine substitution at position 341 (P341S) in the Site 1 protease (S1P) protein. (J:274663)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mbtps1 Mutation: 73 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3999

References

• Original: J:274663 Arnold A, et al., Mutagenetix entry for muskrat. MGI Direct Data Submission. 2019
• All: 1 reference(s)