Postn^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Postn^m1Btlr
• Name: periostin, osteoblast specific factor; mutation 1, Bruce Beutler
• MGI ID: MGI:6304299
• Synonyms: sticklike
• Gene: Postn Location: Chr3:54268530-54298458 bp, + strand Genetic Position: Chr3, 25.46 cM
• Alliance: Postn^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced G to T transversion at base pair 54,372,106 (v38) on chromosome 3, or base pair 12,835 in the GenBank genomic region NC_000069 encoding Postn. The mutation corresponds to residue 1,040 in the mRNA sequence NM_015784 within exon 8 of 22 total exons. The mutation results in a cysteine to phenylalanine substitution at position 335 (C335F) in the periostin protein. (J:274733)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Postn Mutation: 53 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3522

References

• Original: J:274733 Zhang Z, et al., Mutagenetix entry for sticklike. MGI Direct Data Submission. 2019
• All: 1 reference(s)