Xrcc5^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Xrcc5^m1Btlr
• Name: X-ray repair complementing defective repair in Chinese hamster cells 5; mutation 1, Bruce Beutler
• MGI ID: MGI:6304305
• Synonyms: durio
• Gene: Xrcc5 Location: Chr1:72346586-72434111 bp, + strand Genetic Position: Chr1, 36.5 cM, cytoband E
• Alliance: Xrcc5^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transition at base pair 72,339,029 (v38) on chromosome 1, or base pair 31,613 in the GenBank genomic region NC_000067 encoding Xrcc5. The mutation corresponds to residue 1,309 in the mRNA sequence NM_009533 within exon 11 of 21 total exons. The mutation results in a tyrosine (Y) to histidine (H) substitution at position 395 (Y395H) in the Ku80 protein. (J:274736)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Xrcc5 Mutation: 71 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=2741

References

• Original: J:274736 Zhong X, et al., Mutagenetix entry for durio. MGI Direct Data Submission. 2019
• All: 1 reference(s)