Zfp638^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zfp638^em1(IMPC)J
• Name: zinc finger protein 638; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:6304325
• Gene: Zfp638 Location: Chr6:83844050-83963855 bp, + strand Genetic Position: Chr6, 36.06 cM
• Alliance: Zfp638^em1(IMPC)J page
• IMPC: Zfp638 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CTCAAGCTGACAAATCAATT and ATTATCACGCTTGTAAAGAA, which resulted in a 136 bp deletion beginning at Chromosome 6 position 83,934,897 bp and ending after 83,935,032 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000194351 (exon 3) and 74 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 437 and early truncation 2 amino acids later. (J:188991)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Zfp638 Mutation: 78 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 3 reference(s)