Cd8b1^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Cd8b1^m2Btlr
• Name: CD8 subunit beta 1; mutation 2, Bruce Beutler
• MGI ID: MGI:6304443
• Synonyms: denuded
• Gene: Cd8b1 Location: Chr6:71299772-71314476 bp, + strand Genetic Position: Chr6, 32.14 cM
• Alliance: Cd8b1^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to A transversion at base pair 71,326,340 (v38) on chromosome 6, or base pair 3,529 in the GenBank genomic region NC_000072 encoding Cd8b1. The mutation corresponds to residue 467 in the mRNA sequence NM_009858 within exon 2 of 6 total exons. The mutation results in a leucine to glutamine substitution at position 133 (L133Q) in the CD8B1 protein. (J:274761)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd8b1 Mutation: 20 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=4204

References

• Original: J:274761 Zhong X, et al., Mutagenetix entry for denuded. MGI Direct Data Submission. 2019
• All: 1 reference(s)