Bcl3^m3Btlr
Chemically induced Allele Detail

Summary

• Symbol: Bcl3^m3Btlr
• Name: B cell leukemia/lymphoma 3; mutation 3, Bruce Beutler
• MGI ID: MGI:6305105
• Synonyms: memorial
• Gene: Bcl3 Location: Chr7:19542387-19556691 bp, - strand Genetic Position: Chr7, 9.95 cM
• Alliance: Bcl3^m3Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to T transversion at base pair 19,812,484 (v38) on chromosome 7, or base pair 10,284 in the GenBank genomic region NC_000073. The mutation corresponds to residue 503 in the mRNA sequence NM_033601 within exon 3 of 9 total exons. The mutation results in an asparagine to isoleucine substitution at position 142 (N142I) in the BCL3 protein. (J:274858)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcl3 Mutation: 56 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3703

References

• Original: J:274858 Choi JH, et al., Mutagenetix entry for memorial. MGI Direct Data Submission. 2019
• All: 1 reference(s)