Cd3e^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Cd3e^m2Btlr
• Name: CD3 antigen, epsilon polypeptide; mutation 2, Bruce Beutler
• MGI ID: MGI:6305303
• Synonyms: cadence
• Gene: Cd3e Location: Chr9:44910038-44920925 bp, - strand Genetic Position: Chr9, 24.84 cM
• Alliance: Cd3e^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to T transversion at base pair 45,001,128 (v38) on chromosome 9, or base pair 8,537 in the GenBank genomic region NC_000075 encoding Cd3e. The mutation corresponds to residue 416 in the mRNA sequence NM_007648 within exon 6 of 8 total exons. The mutation results in a glutamic acid to valine substitution at position 106 (E106V) in the CD3 protein. (J:274934)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd3e Mutation: 54 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3513

References

• Original: J:274934 Zhong X, et al., Mutagenetix entry for cadence. MGI Direct Data Submission. 2019
• All: 1 reference(s)