Stat1^m5Btlr
Chemically induced Allele Detail

Summary

• Symbol: Stat1^m5Btlr
• Name: signal transducer and activator of transcription 1; mutation 1, Bruce Beutler
• MGI ID: MGI:6305319
• Synonyms: roccoco
• Gene: Stat1 Location: Chr1:52158599-52201024 bp, + strand Genetic Position: Chr1, 26.81 cM
• Alliance: Stat1^m5Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to T transversion at base pair 52,123,209 (v38) on chromosome 1, or base pair 3,772 in the GenBank genomic region NC_000067 encoding Stat1. The mutation corresponds to residue 523 in the mRNA sequence NM_001205313 within exon 4 of 25 total exons. The mutation results in an asparagine to isoleucine substitution at amino acid 75 (N75I) in the STAT1 protein. (J:274938)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stat1 Mutation: 74 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=2759

References

• Original: J:274938 Zhong X, et al., Mutagenetix entry for roccoco. MGI Direct Data Submission. 2019
• All: 1 reference(s)