Klhl6^M8Btlr
Chemically induced Allele Detail

Summary

• Symbol: Klhl6^M8Btlr
• Name: kelch-like 6; mutation 8, Bruce Beutler
• MGI ID: MGI:6305808
• Synonyms: Lazuli
• Gene: Klhl6 Location: Chr16:19765242-19801766 bp, - strand Genetic Position: Chr16, 12.32 cM
• Alliance: Klhl6^M8Btlr page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: AC>C frame shift due to a 1-bp deletion at base pair 19,956,966 (v38) on chromosome 16, or base pair 26,083 in the GenBank genomic regionNC_000082encodingKlhl6.The mutation corresponds to c.888delA in the mRNA sequence NM_183390 within exon 3 of 7 total exons. The mutation is predicted to result in a frame shifted protein product beginning after amino acid 279 and termination after the inclusion of 40 aberrant amino acids. (J:274963)
• Inheritance: Dominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Klhl6 Mutation: 48 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=4369

References

• Original: J:274963 Choi JH, et al., Mutagenetix entry for Lazuli. MGI Direct Data Submission. 2019
• All: 1 reference(s)