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Tg(Adipoq-rtTA)2Zvw
Transgene Detail
Summary
Symbol: Tg(Adipoq-rtTA)2Zvw
Name: transgene inserion 2, Zhao Wang
MGI ID: MGI:6306100
Synonyms: Adiponectin-rtTA, adnP-rtTA, APN-rtTA
Transgene: Tg(Adipoq-rtTA)2Zvw  Location: unknown  
Alliance: Tg(Adipoq-rtTA)2Zvw page
Transgene
origin
Strain of Origin:  C57BL/6N
Transgene
description
Transgene Type:    Transgenic (Transactivator)
Mutation:    Insertion
 
Mutation detailsThe transgene was designed with an adiponection (Adipoq) promoter driving expression of the reverse tetracycline transactivator gene (rtTA). The 5.4 kb adiponectin promoter is comprised of 200 bp from the 5' end of the first intron linked to 200 bp from the 3' end of the first intron. The 3' end of the promoter is extended beyond the endogenous start codon ATG, which is mutated to ATA to facilitate correct translation initiation. (J:183541)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:183541 Sun K, et al., Dichotomous effects of VEGF-A on adipose tissue dysfunction. Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5874-9
All:  20 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory