Lonrf2^em2(IMPC)H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Lonrf2^em2(IMPC)H
• Name: LON peptidase N-terminal domain and ring finger 2; endonuclease-mediated mutation 2, Harwell
• MGI ID: MGI:6306617
• Gene: Lonrf2 Location: Chr1:38832750-38875768 bp, - strand Genetic Position: Chr1, 17.17 cM
• Alliance: Lonrf2^em2(IMPC)H page
• IMPC: Lonrf2 gene page

Mutation origin

• Strain of Origin: C57BL/6NTac
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from IMPC was generated at Medical Research Council Harwell by injecting CAS9 RNA and 4 guide sequences CCCTGAATAATCAAGGACCATGG, CCTGAATAATCAAGGACCATGGG, GATCAAGTTGGTACACATTCAGG, CCCACCATGCCGGCTCTCTTTTT, which resulted in a Exon Deletion. (J:265051)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Lonrf2 Mutation: 44 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 3 reference(s)