Cnot6l^tm1Tya
Targeted Allele Detail

Summary

• Symbol: Cnot6l^tm1Tya
• Name: CCR4-NOT transcription complex, subunit 6-like; targeted mutation 1, Tadashi Yamamoto
• MGI ID: MGI:6306636
• Gene: Cnot6l Location: Chr5:96218192-96312030 bp, - strand Genetic Position: Chr5, 47.29 cM
• Alliance: Cnot6l^tm1Tya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:274297
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• A lacZ reporter and neomycin resistance selection cassette replaced exons 2 through 4. (J:274297)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cnot6l Mutation: 45 strains or lines available

References

• Original: J:274297 Morita M, et al., Hepatic posttranscriptional network comprised of CCR4-NOT deadenylase and FGF21 maintains systemic metabolic homeostasis. Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):7973-7981
• All: 3 reference(s)