Calhm3^em1Jkf
Endonuclease-mediated Allele Detail

Summary

• Symbol: Calhm3^em1Jkf
• Name: calcium homeostasis modulator 3; endonuclease-mediated mutation 1, J Kevin Foskett
• MGI ID: MGI:6307099
• Gene: Calhm3 Location: Chr19:47140138-47146203 bp, - strand Genetic Position: Chr19, 39.37 cM
• Alliance: Calhm3^em1Jkf page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 2315 bp. (J:269649)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Calhm3 Mutation: 4 strains or lines available

References

• Original: J:269649 Ma Z, et al., CALHM3 Is Essential for Rapid Ion Channel-Mediated Purinergic Neurotransmission of GPCR-Mediated Tastes. Neuron. 2018 May 2;98(3):547-561.e10
• All: 2 reference(s)