Pdcd1^{tm1.1(PDCD1)Geno}
Targeted Allele Detail

Summary

• Symbol: Pdcd1^{tm1.1(PDCD1)Geno}
• Name: programmed cell death 1; targeted mutation 1.1, Genoway
• MGI ID: MGI:6315563
• Synonyms: Pdcd1^{tm1.1(hPDCD1)Geno}, Pdcd1^{tm1(huPDCD1-ICP11)Geno}
• Gene: Pdcd1 Location: Chr1:93966027-93980278 bp, - strand Genetic Position: Chr1, 47.47 cM
• Alliance: Pdcd1^{tm1.1(PDCD1)Geno} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:276209
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Humanized sequence, Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The chimeric allele contains human extracellular and mouse intracellular domain. Cre-mediated recombination removed the selection cassette. (J:276209)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 4 strains available Cell Lines: 0 lines available
• Carrying any Pdcd1 Mutation: 99 strains or lines available

Notes

https://www.genoway.com/services/catalog/humanized-mouse/immune-checkpoints.htm

References

• Original: J:276209 Sonego F, Direct Data Submission for Genoway Humanized Immune Checkpoint (ICP) Mice. MGI Direct Data Submission. 2019
• All: 4 reference(s)