Tg(Myh6-DFFB)1Khu
Transgene Detail

Summary

• Symbol: Tg(Myh6-DFFB)1Khu
• Name: transgene insertion 1, Kai Huang
• MGI ID: MGI:6315918
• Transgene: Tg(Myh6-DFFB)1Khu Location: unknown
• Alliance: Tg(Myh6-DFFB)1Khu page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-DFFB)1Khu expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  DFFB (1677)

  Dffb	(MGI:1196287)

• Mutation details: The human DFFB cDNA is under the control of the cardiac alpha-myosin heavy chain promoter. Four lines were generated. This is the highest expressing line. (J:259377)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:259377 Gao L, et al., Novel role for caspase-activated DNase in the regulation of pathological cardiac hypertrophy. Hypertension. 2015 Apr;65(4):871-81
• All: 1 reference(s)