Slc6a4^{em1(flpo)Fuyu}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Slc6a4^{em1(flpo)Fuyu}
• Name: solute carrier family 6 (neurotransmitter transporter, serotonin), member 4; endonuclease-mediated mutation 1, Fu Yu
• MGI ID: MGI:6316965
• Gene: Slc6a4 Location: Chr11:76889429-76923166 bp, + strand Genetic Position: Chr11, 46.18 cM
• Alliance: Slc6a4^{em1(flpo)Fuyu} page

Mutation origin

• Strain of Origin: C57BL/6NCrl

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Slc6a4^{em1(flpo)Fuyu} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Slc6a4 (MGI:96285)

• Mutation details: CRISPR/Cas9-system was used to introduce an internal ribosomal entry site (IRES) and a Flpo recombinase sequence downstream of the stop codon of the solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 (Slc6a4) gene. (J:101977)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Slc6a4 (mouse) Summary of all recombinase alleles driven by Slc6a4. Alliance mouse Slc6a4 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Slc6a4 Mutation: 53 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)