Tg(Lypd6b-cre)1Sleep
Transgene Detail

Summary

• Symbol: Tg(Lypd6b-cre)1Sleep
• Name: transgene insertion 1, Yu Hayashi
• MGI ID: MGI:6317423
• Synonyms: ILN-Cre, Lypd6b-Cre
• Transgene: Tg(Lypd6b-cre)1Sleep Location: unknown
• Alliance: Tg(Lypd6b-cre)1Sleep page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Lypd6b-cre)1Sleep expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Lypd6b (MGI:1919147)

• Mutation details: A bacterial artificial chromosome clone (RP23-116A1) containing the Lypd6b (LY6/PLAUR domain containing 6B) gene was used to generate an ILN-specific Cre transgenic mouse line. (J:276634)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Lypd6b (mouse) Summary of all recombinase alleles driven by Lypd6b. Comparative matrix view of recombinase activities Alliance mouse Lypd6b gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:276634 Yasuda K, et al., Schizophrenia-like phenotypes in mice with NMDA receptor ablation in intralaminar thalamic nucleus cells and gene therapy-based reversal in adults. Transl Psychiatry. 2017 Feb 28;7(2):e1047
• All: 1 reference(s)